Electrochemistry-Enabled Ir-Catalyzed Vinylic C–H Functionalization

• Published in: Journal of the American Chemical Society Vol. 141; no. 48; pp. 18970 - 18976
• Main Authors: Yang, Qi-Liang, Xing, Yi-Kang, Wang, Xiang-Yang, Ma, Hong-Xing, Weng, Xin-Jun, Yang, Xiang, Guo, Hai-Ming, Mei, Tian-Sheng
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 04.12.2019; Amer Chemical Soc
• Subjects: alkynes; aromatic hydrocarbons; carbon-hydrogen bond activation; catalysts; catalytic activity; Chemistry; Chemistry, Multidisciplinary; electric current; electrochemistry; iridium; oxidation; Physical Sciences; Science & Technology; PALLADIUM; ACRYLIC-ACIDS; ANNULATION; ALPHA-PYRONES; BOND ACTIVATION; ISOCOUMARINS; ALKYNES; ACCESS; BENZOIC-ACIDS

Synergistic use of electrochemistry and organometallic catalysis has emerged as a powerful tool for site-selective C–H functionalization, yet this type of transformation has thus far mainly been limited to arene C–H functionalization. Herein, we report the development of electrochemical vinylic C–H...