Mechanistic insights into the kidney injury in chickens induced by hypervirulent fowl adenovirus serotype 4

• Published in: Microbiology spectrum Vol. 13; no. 5; p. e0005825
• Main Authors: Zhu, Chunhua, Zhou, Jiayu, Chen, Zhen, Chen, Cuiteng, Wang, Ziyue, Yang, Pei, Fu, Guanghua, Liu, Xiaodong, Huang, Yu, Wan, Chunhe
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 25.03.2025
• Subjects: autophagosome-like vesicles' delivery; hypervirulent fowl adenovirus serotype 4; inflammation; kidney injury; Research Article; Veterinary Microbiology; autophagosome-like vesicles' delivery; kidney injury; inflammation; hypervirulent fowl adenovirus serotype 4

Hypervirulent fowl adenovirus serotype 4 (FAdV-4) has become globally prevalent since 2015 as a predominant pathogen on poultry farms, leading to substantial economic losses for the poultry industry. However, the molecular mechanisms underlying kidney injury induced by FAdV-4 infection remain unclea...