Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia

• Published in: Archives of neurology (Chicago) Vol. 77; no. 3; p. 358
• Main Authors: Liu, Andy J, Staffaroni, Adam M, Rojas-Martinez, Julio C, Olney, Nicholas T, Alquezar-Burillo, Carolina, Ljubenkov, Peter A, La Joie, Renaud, Fong, Jamie C, Taylor, Joanne, Karydas, Anna, Ramos, Eliana Marisa, Coppola, Giovanni, Boxer, Adam L, Rabinovici, Gil D, Miller, Bruce L, Kao, Aimee W
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 01.03.2020
• Subjects: Adult; Adults; Aged; Amyloid; Biomarkers; Biomarkers - cerebrospinal fluid; Case-Control Studies; Cerebrospinal fluid; Chains; Cognitive ability; Dementia; Dementia disorders; Disorders; Female; Fluorine; Frontotemporal Dementia; Humans; Male; Measuring techniques; Medical imaging; Mental disorders; Middle Aged; Neuroimaging; Neuroimaging - methods; Neuropsychological Tests; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Psychics; Psychology; Signs and symptoms; Tau protein; Tuberous sclerosis; Tuberous Sclerosis - cerebrospinal fluid; Tuberous Sclerosis - complications; Tuberous Sclerosis - pathology

Individuals with tuberous sclerosis complex can develop a progressive neuropsychiatric syndrome known as tuberous sclerosis-associated neuropsychiatric disorders. Tuberous sclerosis-associated neuropsychiatric disorders symptoms overlap with clinical criteria for frontotemporal dementia, yet the ass...