Density Functional Theory Calculation May Confirm Arsenic–Thiol Adhesion as the Primary Mechanism of Arsenical Toxicity

• Published in: ACS omega Vol. 9; no. 12; pp. 13975 - 13981
• Main Authors: Tsai, Meng-Han, Lin, Ying-Ting
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 26.03.2024

Previously, it was believed that methylation was the body’s primary method to detoxify inorganic arsenic. However, recent research has shown that the metabolized intermediate known as MMAIII is more toxic than arsenite and arsenate, contradicting a previous understanding. Another important question...