Initial Characterization of the Viridisins’ Biological Properties

• Published in: ACS omega Vol. 9; no. 29; pp. 31832 - 31841
• Main Authors: Vermeulen, Ross Rayne, van Staden, Anton Du Preez, Ollewagen, Tracey, van Zyl, Leonardo Joaquim, Luo, Youran, van der Donk, Wilfred A., Dicks, Leon Milner Theodore, Smith, Carine, Trindade, Marla
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 23.07.2024

Viridisin A1 and A2 were previously heterologously expressed, purified, and characterized as ribosomally produced and post-translationally modified lanthipeptides. Such lanthipeptide operons are surprisingly common in Gram-negative bacteria, although their expression seems to be predominantly crypti...