Core–Shell Plasmonic Nanomaterials toward: Dual-Mode Imaging Analysis of Glutathione and Enhanced Chemodynamic Therapy

• Published in: Analytical chemistry (Washington) Vol. 93; no. 29; pp. 10317 - 10325
• Main Authors: Wang, Jin, Liu, Ying-Xue, Li, Xiang-Ling, Chen, Hong-Yuan, Xu, Jing-Juan
• Format: Journal Article
• Language: English
• Published: Washington American Chemical Society 27.07.2021
• Subjects: adverse effects; Analytical chemistry; Cancer; cancer therapy; Chemistry; Deoxyribonucleic acid; DNA; DNA probes; Fluorescence; fluorescent dyes; Glutathione; Information processing; Intracellular; light microscopes; Manganese dioxide; Medical imaging; Nanomaterials; Nanoparticles; nanosheets; Nanotechnology; Optical microscopes; Optical properties; Plasmonics; Switching; Therapy

A simple process, rich information, and intelligent response are the goals pursued by cancer diagnosis and treatment. Herein, we developed a core–shell plasmonic nanomaterial (Au@MnO2-DNA), which consisted of a AuNP core with an outer shell MnO2 nanosheet decorated with fluorophore modified DNA, to...