Ultralow Background Membrane Editors for Spatiotemporal Control of Phosphatidic Acid Metabolism and Signaling

• Published in: ACS central science Vol. 10; no. 3; pp. 543 - 554
• Main Authors: Li, Xiang-Ling, Tei, Reika, Uematsu, Masaaki, Baskin, Jeremy M.
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 27.03.2024

Phosphatidic acid (PA) is a multifunctional lipid with important metabolic and signaling functions, and efforts to dissect its pleiotropy demand strategies for perturbing its levels with spatiotemporal precision. Previous membrane editing approaches for generating local PA pools used light-mediated...