Efficacy of Skin and Nasal Povidone-Iodine Preparation against Mupirocin-Resistant Methicillin-Resistant Staphylococcus aureus and S. aureus within the Anterior Nares

• Published in: Antimicrobial agents and chemotherapy Vol. 59; no. 5; pp. 2765 - 2773
• Main Authors: Anderson, Michele J., David, Maren L., Scholz, Matt, Bull, Sally J., Morse, Dan, Hulse-Stevens, Michelle, Peterson, Marnie L.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.05.2015
• Subjects: Animals; Experimental Therapeutics; Humans; In Vitro Techniques; Methicillin-Resistant Staphylococcus aureus; Methicillin-Resistant Staphylococcus aureus - drug effects; Methicillin-Resistant Staphylococcus aureus - pathogenicity; Mupirocin; Mupirocin - therapeutic use; Nose; Nose - microbiology; Povidone-Iodine; Povidone-Iodine - therapeutic use; Skin; Skin - microbiology; Staphylococcus aureus; Swine
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.04624-14

Mupirocin decolonization of nasal Staphylococcus aureus prior to surgery decreases surgical-site infections; however, treatment requires 5 days, compliance is low, and resistance occurs. In 2010, 3M Company introduced povidone-iodine (PVP-I)-based skin and nasal antiseptic (Skin and Nasal Prep [SNP]...