Evaluating the Pharmacodynamic Effect of Antimalarial Drugs in Clinical Trials by Quantitative PCR - Marquart, Louise; Baker, Mark; O'Rourke, Peter; McCarthy, James S. (Antimicrobial agents and chemotherapy, 2015)
Keywords: Adolescent; Adult; Algorithms; Antimalarials; Antimalarials - adverse effects; Antimalarials - pharmacokinetics; Antimalarials - therapeutic use; Area Under Curve; Drug Combinations; Female; Half-Life; Humans; Malaria; Malaria - drug therapy; Malaria - parasitology; Male; Mefloquine - adverse effects; Mefloquine - pharmacokinetics; Mefloquine - therapeutic use; Models, Statistical; Parasitemia - drug therapy; Parasitemia - parasitology; Pharmacology; Polymerase Chain Reaction; Polymerase Chain Reaction - methods; Pyrimethamine - adverse effects; Pyrimethamine - pharmacokinetics; Pyrimethamine - therapeutic use; Reproducibility of Results; Sulfadoxine - adverse effects; Sulfadoxine - pharmacokinetics; Sulfadoxine - therapeutic use; Young Adult; Australia; PSE, New Zealand