SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV‑2 in Clinical Samples

• Published in: ACS applied bio materials Vol. 4; no. 4; pp. 2974 - 2995
• Main Authors: Yadav, Shalu, Sadique, Mohd. Abubakar, Ranjan, Pushpesh, Kumar, Neeraj, Singhal, Ayushi, Srivastava, Avanish K, Khan, Raju
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 19.04.2021
• Subjects: Antibodies, Immobilized - chemistry; Antibodies, Immobilized - immunology; Antibodies, Viral - blood; Antibodies, Viral - immunology; Biomarkers - blood; Biomarkers - metabolism; COVID-19 - diagnosis; COVID-19 - virology; Humans; Immunoassay - methods; Point-of-Care Systems; Review; SARS-CoV-2 - isolation & purification; SARS-CoV-2 - metabolism; Spectrum Analysis, Raman; Viral Proteins - immunology; Viral Proteins - metabolism; COVID-19; POC devices; SARS-CoV-2; lateral flow immunoassay; surface-enhanced Raman spectroscopy

The current scenario, an ongoing pandemic of COVID-19, places a dreadful burden on the healthcare system worldwide. Subsequently, there is a need for a rapid, user-friendly, and inexpensive on-site monitoring system for diagnosis. The early and rapid diagnosis of SARS-CoV-2 plays an important role i...