Porphyrin-Based Nanomedicines for Cancer Treatment

• Published in: Bioconjugate chemistry Vol. 30; no. 6; pp. 1585 - 1603
• Main Authors: Xue, Xiangdong, Lindstrom, Aaron, Li, Yuanpei
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 19.06.2019
• Subjects: Animals; Cancer; Cancer therapies; Computed tomography; Diagnostic systems; Fluoroscopic imaging; Humans; Hyperthermia, Induced - methods; Infrared imaging; Liposomes; Liposomes - chemistry; Liposomes - therapeutic use; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Medical imaging; Micelles; Models, Molecular; Nanoparticles; Nanoparticles - chemistry; Nanoparticles - therapeutic use; Neoplasms - diagnostic imaging; Neoplasms - therapy; NMR; Nuclear magnetic resonance; Optical Imaging - methods; Photochemotherapy - methods; Photon emission; Porphyrins; Porphyrins - chemistry; Porphyrins - therapeutic use; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Single photon emission computed tomography; Theranostic Nanomedicine - methods; Tomography; Tomography, Emission-Computed, Single-Photon - methods

As unique molecules with both therapeutic and diagnostic properties, porphyrin derivatives have been extensively employed for cancer treatment. Porphyrins not only show powerful phototherapeutic effects (photodynamic and photothermal therapies), but also exhibit excellent imaging capacities, such as...