Discovery and Validation of Plasma Biomarkers for Major Depressive Disorder Classification Based on Liquid Chromatography–Mass Spectrometry - Liu, Xinyu; Zheng, Peng; Zhao, Xinjie; Zhang, Yuqing; Hu, Chunxiu; Li, Jia; Zhao, Jieyu; Zhou, Jingjing; Xie, Peng; Xu, Guowang (Journal of proteome research, 2015)
Keywords: Adult; biomarkers; Biomarkers - blood; carnitine; Carnitine - analogs & derivatives; Carnitine - blood; Case-Control Studies; Chromatography, Liquid; Depressive Disorder, Major - blood; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - physiopathology; Female; Humans; Lipid Metabolism; lipids; Logistic Models; Lysophosphatidylcholines - blood; Lysophospholipids - blood; Male; mass spectrometry; mental depression; metabolites; Metabolome; metabolomics; Middle Aged; monitoring; patients; Phosphatidylethanolamines - blood; proteome; Quality of Life; regression analysis; Sensitivity and Specificity; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tryptophan; Tryptophan - analogs & derivatives; Tryptophan - blood; ultra-performance liquid chromatography; major depressive disorder; LC−MS; metabolomics; diagnosis biomarker