Serum Endoglin Levels in Patients Suffering from Systemic Sclerosis and Elevated Systolic Pulmonary Arterial Pressure

• Published in: International Journal of Rheumatology Vol. 2010; no. 2010; pp. 152 - 157
• Main Authors: Garces, Maria Fernanda, Coral-Alvarado, Paola Ximena, Caminos, Jorge Eduardo, Iglesias-Gamarra, Antonio, Restrepo, José Félix, Quintana, Gerardo
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 2010; Hindawi Puplishing Corporation; Hindawi Publishing Corporation; John Wiley & Sons, Inc
• Subjects: Apoptosis; Biomarkers; Clinical Study; Extracellular matrix; Fibroblasts; Hypertension; Lung diseases; Medical prognosis; Mortality; Pathogenesis; Patients; Rheumatology; Rodents; Ultrasonic imaging

Background. Pulmonary arterial hypertension (PAH) is the main cause of morbimortality in systemic sclerosis (SSc). Increased Eng expression has been demonstrated in SSc patients. Objective. Ascertaining serum levels of Eng in SSc patients with and without elevated systolic pulmonary arterial pressur...