Absolute Configuration and Biological Activities of Meroterpenoids from an Endophytic Fungus of Lycium barbarum

• Published in: Journal of natural products (Washington, D.C.) Vol. 82; no. 8; pp. 2229 - 2237
• Main Authors: Long, Yi, Tang, Ting, Wang, Li-Ying, He, Bin, Gao, Kun
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society and American Society of Pharmacognosy 23.08.2019; Amer Chemical Soc
• Subjects: benzoquinones; biosynthesis; Bipolaris; Chemistry, Medicinal; cytotoxicity; endophytes; fungi; hydroquinone; inhibitory concentration 50; Life Sciences & Biomedicine; Lycium barbarum; meroterpenoids; moieties; Pharmacology & Pharmacy; Plant Sciences; Science & Technology; spectral analysis; X-ray diffraction; POTENTIATORS; STEMPHONES

Eleven new meroterpenoids, bipolahydroquinones A–C (1–3), cochlioquinones I–N (4–8 and 11), and isocochlioquinones F and G (9 and 10), together with six known ones, were obtained from an endophytic fungus Bipolaris sp. L1-2 from Lycium barbarum. Compound 2 is the first example of cochlioquinone deri...