Isolation, Structural Elucidation, Optical Resolution, and Antineuroinflammatory Activity of Phenanthrene and 9,10-Dihydrophenanthrene Derivatives from Bletilla striata

• Published in: Journal of natural products (Washington, D.C.) Vol. 82; no. 8; pp. 2238 - 2245
• Main Authors: Zhou, Di, Chen, Gang, Ma, Yue-Ping, Wang, Cun-Gang, Lin, Bin, Yang, Yan-Qiu, Li, Wei, Koike, Kazuo, Hou, Yue, Li, Ning
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society and American Society of Pharmacognosy 23.08.2019; Amer Chemical Soc
• Subjects: Bletilla striata; Chemistry, Medicinal; enantiomers; ethanol; inhibitory concentration 50; Life Sciences & Biomedicine; neuroglia; nitric oxide; Pharmacology & Pharmacy; phenanthrenes; phytochemicals; Plant Sciences; Science & Technology; spectroscopy; tubers; DIHYDROPHENANTHRENES; BIBENZYLS; TUBERS; GLUCOSIDES; CONSTITUENTS

A phytochemical investigation of the aqueous EtOH extract of Bletilla striata tubers afforded 34 phenanthrene and 9,10-dihydrophenanthrene derivatives, including four new compounds, 1–4. These compounds were identified using physicochemical analyses and various spectroscopic methods. Twelve of these...