The inhibitory receptor LAG3 affects NK cell IFN-γ production through glycolysis and the PSAT1/STAT1/IFNG pathway - Ge, Hongchi; Guo, Nan; Liu, Yufei; Lang, Bin; Yin, Xiaowan; Yu, Xiaowen; Zhang, Zining; Fu, Yajing; Ding, Haibo; Hu, Qinghai; Han, Xiaoxu; Geng, Wenqing; et al. (mBio, 2025)
Keywords: Antigens, CD - genetics; Antigens, CD - immunology; Antigens, CD - metabolism; Female; Glycolysis; HIV; HIV Infections - immunology; Humans; IFN-γ; Immunology; Interferon-gamma - metabolism; Killer Cells, Natural - immunology; Killer Cells, Natural - metabolism; LAG3; Lymphocyte Activation Gene 3 Protein; Male; Research Article; Signal Transduction; STAT1; STAT1 Transcription Factor - genetics; STAT1 Transcription Factor - metabolism; IFN-γ; LAG3; HIV; STAT1; NK; glycolysis