Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β‑Unsaturated Carbonyl Derivatives

Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn­(I) complex as a catalyst. Through H–P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-bas...

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Bibliographic Details
Published inOrganic letters Vol. 25; no. 10; pp. 1611 - 1615
Main Authors Postolache, Roxana, Pérez, Juana M., Castiñeira Reis, Marta, Ge, Luo, Sinnema, Esther G., Harutyunyan, Syuzanna R.
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 17.03.2023
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Letter
Physical Sciences
Science & Technology
DIARYLPHOSPHINES
CATALYSIS
ALKENES
DIPHOSPHINES
LIGANDS
PHOSPHINES
1,4-ADDITION
ALKYNES
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Summary:Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn­(I) complex as a catalyst. Through H–P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-based Michael acceptors.
Bibliography:European Research Council (ERC)
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.2c04256