Prevotella copri variants among a single host diverge in sphingolipid production

• Published in: mBio Vol. 15; no. 2; p. e0240923
• Main Authors: Xiao, Xieyue, Le, Henry H, Lee, Min-Ting, Lamm, Daniel, Johnson, Elizabeth L, Brito, Ilana L
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 14.02.2024
• Subjects: Host-Microbial Interactions; host–microbe interactions; microbiome; Prevotella; Prevotella copri; Research Article; sphingolipids; Prevotella copri; Prevotella; host–microbe interactions; sphingolipids; microbiome

Sphingolipids serve as vital structural and signaling components of the cell membranes in both eukaryotes and prokaryotes. Within the gut microbiome, species have been identified as major producers of sphingolipids, and -produced sphingolipids have been shown to be modulators of host immune and meta...