The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach?

• Published in: ACS infectious diseases Vol. 3; no. 8; pp. 559 - 563
• Main Authors: Melander, Roberta J, Melander, Christian
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 11.08.2017
• Subjects: Adjuvants, Pharmaceutic - pharmacology; Animals; Anti-Bacterial Agents - pharmacology; Drug Interactions; Drug Resistance, Bacterial - drug effects; Drug Resistance, Bacterial - physiology; Gram-Negative Bacteria - drug effects; Gram-Negative Bacteria - growth & development; Gram-Negative Bacteria - metabolism; Gram-Positive Bacteria - drug effects; Gram-Positive Bacteria - growth & development; Gram-Positive Bacteria - metabolism; Humans

Antibiotic resistance is one of the greatest current threats to human health, and without significant action we face the chilling prospect of a world without effective antibiotics. Although continued effort toward the development of new antibiotics, particularly those with novel mechanisms of action...