Real-Time 2D NMR Identification of Analytes Undergoing Continuous Chromatographic Separation

• Published in: Journal of the American Chemical Society Vol. 126; no. 4; pp. 1262 - 1265
• Main Authors: Shapira, Boaz, Karton, Amir, Aronzon, Dina, Frydman, Lucio
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 04.02.2004
• Subjects: Analytical chemistry; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography, Liquid - instrumentation; Chromatography, Liquid - methods; Exact sciences and technology; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Other chromatographic methods; Separation method; Analysis method; Coupled method; Homonuclear correlation; Liquid chromatography; NMR spectrometry; Two dimension spectrometry

We have recently proposed and demonstrated an approach that enables the acquisition of multidimensional nuclear magnetic resonance (NMR) spectra within a single scan. A promising application opened up by this new accelerated form of data acquisition concerns the possibility of monitoring in real tim...