Visible-Light Photoredox Borylation of Aryl Halides and Subsequent Aerobic Oxidative Hydroxylation

• Published in: Organic letters Vol. 18; no. 20; pp. 5248 - 5251
• Main Authors: Jiang, Min, Yang, Haijun, Fu, Hua
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 21.10.2016; Amer Chemical Soc
• Subjects: chemical structure; Chemistry; Chemistry, Organic; esters; hydroxylation; organic halogen compounds; phenols; photocatalysts; Physical Sciences; redox reactions; Science & Technology; METAL-FREE BORYLATION; PALLADIUM-CATALYZED BORYLATION; ROOM-TEMPERATURE; CROSS-COUPLING REACTIONS; BOND FUNCTIONALIZATION; SYNTHETIC APPLICATIONS; C-H BORYLATION; ALKOXY DIBORON REAGENTS; AROMATIC-SUBSTITUTION; ARYLBORONIC ACIDS

Efficient and practical visible-light photoredox borylation of aryl halides and subsequent aerobic oxidative hydroxylation were developed. The protocols use readily available aryl halides and bis­(pinacolato)­diboron as the starting materials, fac-Ir­(ppy)3 as the photocatalyst, and corresponding ar...