Ruthenium-Catalyzed Cross-Selective Asymmetric Oxidative Coupling of Arenols

• Published in: Organic letters Vol. 22; no. 4; pp. 1469 - 1474
• Main Authors: Hayashi, Hiroki, Ueno, Takamasa, Kim, Chungsik, Uchida, Tatsuya
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 21.02.2020; Amer Chemical Soc
• Subjects: catalytic activity; chemical bonding; chemical structure; Chemistry; Chemistry, Organic; chemoselectivity; cross-coupling reactions; enantioselectivity; naphthols; oxidation; Physical Sciences; ruthenium; Science & Technology; BINOL; DUAL ACTIVATION; 2-NAPHTHOL DERIVATIVES; PHENOLS; KINETIC RESOLUTION; BINAPHTHOL DERIVATIVES; OXOVANADIUM(IV) COMPLEXES

(Aqua)­ruthenium­(salen) complex 1c achieved good to high chemo- and enantioselective oxidative cross-coupling of arenols. The catalytic system can be used to selectively produce C 1-symmetric bis­(arenol)­s from the combination of C3- and C7-substituted 2-naphthols or phenols even when there is no...