Injectable Peptide Hydrogels Loaded with Murine Embryonic Stem Cells Relieve Ischemia In Vivo after Myocardial Infarction

• Published in: Biomacromolecules Vol. 25; no. 2; pp. 1319 - 1329
• Main Authors: Roy, Abhishek, Hao, Lei, Francisco, Jamie, Guan, Jin, Mareedu, Satvik, Zhai, Peiyong, Dodd-o, Joseph, Heffernan, Corey, Del Re, Dominic, Lee, Eun Jung A., Kumar, Vivek A.
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 12.02.2024
• Subjects: Animals; Embryonic Stem Cells; Hydrogels - pharmacology; Mice; Myocardial Infarction - therapy; Myocardium; Peptides - pharmacology

Myocardial infarction (MI) is a major cause of morbidity and mortality worldwide, especially in aging and metabolically unhealthy populations. A major target of regenerative tissue engineering is the restoration of viable cardiomyocytes to preserve cardiac function and circumvent the progression to...