A Protein Tyrosine Phosphatase 1B Activity Inhibitor from the Fruiting Bodies of Ganoderma lucidum (Fr.) Karst and Its Hypoglycemic Potency on Streptozotocin-Induced Type 2 Diabetic Mice - Teng, Bao-Song; Wang, Chen-Dong; Yang, Hong-Jie; Wu, Jia-Sheng; Zhang, Dan; Zheng, Min; Fan, Zhao-Hua; Pan, Deng; Zhou, Ping (Journal of agricultural and food chemistry, 2011)
Keywords: Animals; Bioactive Constituents; Biological Factors - administration & dosage; Biological Factors - analysis; Biological Factors - isolation & purification; blood glucose; Blood Glucose - analysis; Diabetes Mellitus, Type 2 - drug therapy; Disease Models, Animal; drug therapy; Enzyme Inhibitors - administration & dosage; Enzyme Inhibitors - analysis; Enzyme Inhibitors - isolation & purification; foods; fruiting bodies; Fruiting Bodies, Fungal - chemistry; Ganoderma lucidum; Humans; Hypoglycemic Agents - administration & dosage; Hypoglycemic Agents - analysis; Hypoglycemic Agents - isolation & purification; inhibitory concentration 50; Male; metformin; Mice; molecular weight; noninsulin-dependent diabetes mellitus; Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors; protein-tyrosine-phosphatase; proteoglycans; Reishi - chemistry; Streptozocin; toxicity; Ganoderma lucidum; protein tyrosine phosphatase 1B; inhibitor; diabetes