High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure - Unemo, Magnus; Golparian, Daniel; Nicholas, Robert; Ohnishi, Makoto; Gallay, Anne; Sednaoui, Patrice (Antimicrobial Agents and Chemotherapy, 2012)
Keywords: Alleles; Amino Acid Sequence; Anti-Bacterial Agents; Anti-Bacterial Agents - administration & dosage; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial diseases; Bacterial diseases of the genital system; Biological and medical sciences; Biomarkers - analysis; Cefixime; Cefixime - administration & dosage; Ceftriaxone; Ceftriaxone - administration & dosage; Cephalosporin Resistance; Cephalosporin Resistance - drug effects; Cephalosporin Resistance - genetics; Epidemiology. Vaccinations; France; General aspects; Gonorrhea; Gonorrhea - drug therapy; Gonorrhea - microbiology; Human bacterial diseases; Humans; Infectious diseases; Male; Mechanisms of Resistance; Medical sciences; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Mosaicism; Multilocus Sequence Typing; Neisseria gonorrhoeae; Neisseria gonorrhoeae - drug effects; Neisseria gonorrhoeae - genetics; Neisseria gonorrhoeae - isolation & purification; Pharmacology. Drug treatments; Population Surveillance; Porins - analysis; Porins - genetics; Treatment Failure; France; Europe; Clonality; β-Lactams; Neisseriaceae; Ceftriaxone; Infection; Resistance; Cephalosporin derivatives; Allele; Antibiotic; Sexually transmitted disease; Gonococcal infection; Neisseria gonorrhoeae; Treatment; Bacteriosis; Bacteria; Micrococcales; Genetics; Mosaicism; Antibacterial agent; Cefixime; Failure; Clone; International