Is DNA a Good Model Polymer?

• Published in: Macromolecules Vol. 46; no. 20; pp. 8369 - 8382
• Main Authors: Tree, Douglas R, Muralidhar, Abhiram, Doyle, Patrick S, Dorfman, Kevin D
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 22.10.2013
• Subjects: algorithms; Analytical, structural and metabolic biochemistry; Applied sciences; Biological and medical sciences; diffusivity; DNA; Dna, deoxyribonucleoproteins; Exact sciences and technology; Fundamental and applied biological sciences. Psychology; Gibbs free energy; ionic strength; Miscellaneous; molecular weight; Natural polymers; Nucleic acids; Physicochemistry of polymers; polymers; Molecular rigidity; Monte Carlo method; Double stranded DNA; Hydrodynamic radius; Computer simulation; Theoretical study; Persistence length; Single stranded DNA; Aqueous solution; Diffusion coefficient; Form factor; Conformation

The details surrounding the crossover from wormlike-specific to universal polymeric behavior has been the subject of debate and confusion even for the simple case of a dilute, unconfined wormlike chain. We have directly computed the polymer size, form factor, free energy, and Kirkwood diffusivity fo...