Heterogeneity in the Folding of Villin Headpiece Subdomain HP36

Small single domain proteins that fold on the microsecond time scale have been the subject of intense interest as models for probing the complexity of folding energy landscapes. The villin headpiece subdomain (HP36) has been extensively studied because of its simple three helix structure, ultrafast...

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Bibliographic Details
Published inThe journal of physical chemistry. B Vol. 122; no. 49; pp. 11640 - 11648
Main Authors Nagarajan, Sureshbabu, Xiao, Shifeng, Raleigh, Daniel P, Dyer, R. Brian
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 13.12.2018
Subjects
Kinetics
Microfilament Proteins - chemistry
Molecular Dynamics Simulation
Protein Folding
Spectroscopy, Fourier Transform Infrared
Temperature
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