Arsenic Binding to Proteins

An overview of how arsenic binds to proteins is presented from an analytical and biochemical perspective. The binding affinity, kinetics and speciation of arsenic binding are also investigated.

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Bibliographic Details
Published in	Chemical reviews Vol. 113; no. 10; pp. 7769 - 7792
Main Authors	Shen, Shengwen, Li, Xing-Fang, Cullen, William R, Weinfeld, Michael, Le, X. Chris
Format	Journal Article
Language	English
Published	United States American Chemical Society 09.10.2013
Subjects	Analytical chemistry Animals Apoptosis - drug effects Arsenic Arsenic - chemistry Arsenic - metabolism Biochemistry DNA Repair Enzymes - antagonists & inhibitors DNA Repair Enzymes - metabolism Hemoglobins - chemistry Hemoglobins - metabolism Kinetics Metallothionein - metabolism Protein Binding Proteins Proteins - chemistry Proteins - metabolism Pyruvate Dehydrogenase Complex - antagonists & inhibitors Pyruvate Dehydrogenase Complex - metabolism Review Speciation Thioredoxins - chemistry Thioredoxins - metabolism
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Abstract	An overview of how arsenic binds to proteins is presented from an analytical and biochemical perspective. The binding affinity, kinetics and speciation of arsenic binding are also investigated.
AbstractList	An overview of how arsenic binds to proteins is presented from an analytical and biochemical perspective. The binding affinity, kinetics and speciation of arsenic binding are also investigated.
Author	Weinfeld, Michael Li, Xing-Fang Shen, Shengwen Cullen, William R Le, X. Chris
AuthorAffiliation	University of British Columbia University of Alberta
AuthorAffiliation_xml	– name: University of Alberta – name: University of British Columbia
Author_xml	– sequence: 1 givenname: Shengwen surname: Shen fullname: Shen, Shengwen – sequence: 2 givenname: Xing-Fang surname: Li fullname: Li, Xing-Fang – sequence: 3 givenname: William R surname: Cullen fullname: Cullen, William R – sequence: 4 givenname: Michael surname: Weinfeld fullname: Weinfeld, Michael – sequence: 5 givenname: X. Chris surname: Le fullname: Le, X. Chris email: xc.le@ualberta.ca
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/23808632$$D View this record in MEDLINE/PubMed
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Snippet	An overview of how arsenic binds to proteins is presented from an analytical and biochemical perspective. The binding affinity, kinetics and speciation of...
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SubjectTerms	Analytical chemistry Animals Apoptosis - drug effects Arsenic Arsenic - chemistry Arsenic - metabolism Biochemistry DNA Repair Enzymes - antagonists & inhibitors DNA Repair Enzymes - metabolism Hemoglobins - chemistry Hemoglobins - metabolism Kinetics Metallothionein - metabolism Protein Binding Proteins Proteins - chemistry Proteins - metabolism Pyruvate Dehydrogenase Complex - antagonists & inhibitors Pyruvate Dehydrogenase Complex - metabolism Review Speciation Thioredoxins - chemistry Thioredoxins - metabolism
Title	Arsenic Binding to Proteins
URI	http://dx.doi.org/10.1021/cr300015c https://www.ncbi.nlm.nih.gov/pubmed/23808632 https://www.proquest.com/docview/1477532583 https://www.proquest.com/docview/1464492772 https://pubmed.ncbi.nlm.nih.gov/PMC3797521
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