Cell Survival and Cell Death at the Intersection of Autophagy and Apoptosis: Implications for Current and Future Cancer Therapeutics

• Published in: ACS pharmacology & translational science Vol. 4; no. 6; pp. 1728 - 1746
• Main Authors: Bata, Nicole, Cosford, Nicholas D. P
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 10.12.2021
• Subjects: Review; apoptosis; autophagy

Autophagy and apoptosis are functionally distinct mechanisms for cytoplasmic and cellular turnover. While these two pathways are distinct, they can also regulate each other, and central components of the apoptosis or autophagy pathway regulate both processes directly. Furthermore, several upstream s...