Hydrophobic Drug-Triggered Self-Assembly of Nanoparticles from Silk-Elastin-Like Protein Polymers for Drug Delivery - Xia, Xiao-Xia; Wang, Ming; Lin, Yinan; Xu, Qiaobing; Kaplan, David L (Biomacromolecules, 2014)
Keywords: Antineoplastic agents; Applied sciences; Biological and medical sciences; Cell Line, Tumor - drug effects; Chemotherapy; confocal laser scanning microscopy; cytotoxicity; doxorubicin; Doxorubicin - administration & dosage; Doxorubicin - chemistry; Drug Carriers - chemistry; Drug Delivery Systems; elastin; Elastin - chemistry; endocytosis; Exact sciences and technology; flow cytometry; Humans; Hydrophobic and Hydrophilic Interactions; hydrophobicity; in vitro studies; inhibitory concentration 50; Medical sciences; Microscopy, Atomic Force; nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - chemistry; Natural polymers; neoplasm cells; Neoplasms - drug therapy; Pharmacology. Drug treatments; Physicochemistry of polymers; polymers; Polymers - chemistry; Proteins; silk; Silk - chemistry; Biological properties; Nanoparticle; Control release polymer; Elastin; Cytotoxicity; Drug carrier; Experimental study; Doxorubicin; In vitro; Hela cell line; Nanoencapsulation; Biological activity; Silk; Biomimetic compound; Internalization; Molecular aggregation; Recombinant protein; Aqueous solution; Subcellular distribution; Tumor cell; Release