Neuroprotective and Neurotherapeutic Effects of Tetrahedral Framework Nucleic Acids on Parkinson’s Disease in Vitro - Cui, Weitong; Zhan, Yuxi; Shao, Xiaoru; Fu, Wei; Xiao, Dexuan; Zhu, Junyao; Qin, Xin; Zhang, Tianyi; Zhang, Mei; Zhou, Yi; Lin, Yunfeng (ACS applied materials & interfaces, 2019)
Keywords: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein - metabolism; Animals; apoptosis; Apoptosis - drug effects; bcl-2-Associated X Protein - metabolism; biomarkers; Caspase 3 - metabolism; cell differentiation; cell proliferation; disease control; ganglia; genes; Lewy bodies; Lewy Bodies - drug effects; Lewy Bodies - metabolism; mechanism of action; mitochondria; Mitochondria - drug effects; Mitochondria - metabolism; nanomaterials; neurites; Neuroprotective Agents - pharmacology; Neuroprotective Agents - therapeutic use; nucleic acids; Nucleic Acids - pharmacology; Nucleic Acids - therapeutic use; Parkinson disease; Parkinson Disease - drug therapy; PC12 Cells; phosphatidylinositol 3-kinase; proteins; Proto-Oncogene Proteins c-akt - metabolism; Rats; Reproducibility of Results; Signal Transduction - drug effects; PC12; tetrahedral framework nucleic acids; Parkinson’s disease; α-synuclein; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine