Tetrahedral Framework Nucleic Acid Promotes the Treatment of Bisphosphonate-Related Osteonecrosis of the Jaws by Promoting Angiogenesis and M2 Polarization - Zhao, Dan; Cui, Weitong; Liu, Mengting; Li, Jiajie; Sun, Yue; Shi, Sirong; Lin, Shiyu; Lin, Yunfeng (ACS applied materials & interfaces, 2020)
Keywords: angiogenesis; Animals; bacterial infections; Biological and Medical Applications of Materials and Interfaces; Bisphosphonate-Associated Osteonecrosis of the Jaw - drug therapy; Bisphosphonate-Associated Osteonecrosis of the Jaw - pathology; Bone Density Conservation Agents - chemical synthesis; Bone Density Conservation Agents - chemistry; Bone Density Conservation Agents - pharmacology; bone metabolism; cell proliferation; Cells, Cultured; Humans; hypercalcemia; immune response; ischemia; macrophages; Macrophages - drug effects; Macrophages - pathology; Male; Mice; Molecular Conformation; Neovascularization, Pathologic - drug therapy; Neovascularization, Pathologic - pathology; nucleic acids; Nucleic Acids - chemical synthesis; Nucleic Acids - chemistry; Nucleic Acids - pharmacology; osteonecrosis; osteoporosis; Particle Size; quality of life; Rats; Rats, Wistar; RAW 264.7 Cells; Surface Properties; toxicity; macrophages; tetrahedral framework nucleic acid; endothelia cells; bisphosphonate-related osteonecrosis of the jaws; angiogenesis; M1/M2 polarization