Gastrointestinal Motility Variation and Implications for Plasma Level Variation: Oral Drug Products - Talattof, Arjang; Price, Judy C; Amidon, Gordon L (Molecular pharmaceutics, 2016)
Keywords: Administration, Oral; Anticholesteremic Agents - administration & dosage; Anticholesteremic Agents - blood; Anticholesteremic Agents - pharmacokinetics; Computer Simulation; Diethylcarbamazine - administration & dosage; Diethylcarbamazine - blood; Diethylcarbamazine - pharmacokinetics; Fatty Acids, Monounsaturated - administration & dosage; Fatty Acids, Monounsaturated - blood; Fatty Acids, Monounsaturated - pharmacokinetics; Fluorouracil - administration & dosage; Fluorouracil - blood; Fluorouracil - pharmacokinetics; Gastric Emptying - drug effects; Gastrointestinal Motility - drug effects; Gastrointestinal Transit - drug effects; Humans; Immunosuppressive Agents - administration & dosage; Immunosuppressive Agents - blood; Immunosuppressive Agents - pharmacokinetics; Indoles - administration & dosage; Indoles - blood; Indoles - pharmacokinetics; Intestinal Absorption - drug effects; Lipoxygenase Inhibitors - administration & dosage; Lipoxygenase Inhibitors - blood; Lipoxygenase Inhibitors - pharmacokinetics; Male; Models, Biological; Tissue Distribution; oral dosage; motility; migrating motor complex; mechanistic physiological model; gastric emptying; bioequivalence; clinical trial simulation