Acid Activation in Phenyliodine Dicarboxylates: Direct Observation, Structures, and Implications

• Published in: Journal of the American Chemical Society Vol. 138; no. 39; pp. 12747 - 12750
• Main Authors: Izquierdo, Susana, Essafi, Stéphanie, del Rosal, Iker, Vidossich, Pietro, Pleixats, Roser, Vallribera, Adelina, Ujaque, Gregori, Lledós, Agustí, Shafir, Alexandr
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 05.10.2016; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Science & Technology; IODIDES; CROWN-ETHER COMPLEXES; PRODUCTS; ARYLATION; CHEMISTRY; BOND FORMATION; POLYVALENT IODINE; HYPERVALENT IODINE(III) REAGENT

The use of the hypervalent iodine reagents in oxidative processes has become a staple in modern organic synthesis. Frequently, the reactivity of λ3 iodanes is further enhanced by acids (Lewis or Brønsted). The origin of such activation, however, has remained elusive. Here, we use the common combinat...