Molecular recognition in water: new receptors for adenine derivatives

Individual base pairs between nucleic acid components are generally not observed in water, since the entropic price of bi-molecular association is generally not paid by the newly formed intermolecular hydrogen bonds. Accordingly, such interactions are studied in contexts where other forces are invol...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American Chemical Society Vol. 115; no. 2; pp. 797 - 798
Main Authors Rotello, Vincent M, Viani, Elisabetta A, Deslongchamps, Ghislain, Murray, Brian A, Rebek, Julius
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 01.01.1993
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Multidisciplinary
Exact sciences and technology
General and physical chemistry
Physical Sciences
Science & Technology
Solubility
Solutions
SITE
ACID
SUPPRESSION
BINDING
EFFICIENT
SOLVENT
Adenine derivatives
Solubility
Molecular association
Association constant
Chemical properties
Aqueous solution
Experimental study
Nucleic acid
Organic compounds
Online AccessGet full text

Cover

More Information
Summary:Individual base pairs between nucleic acid components are generally not observed in water, since the entropic price of bi-molecular association is generally not paid by the newly formed intermolecular hydrogen bonds. Accordingly, such interactions are studied in contexts where other forces are involved, and interpretation is difficult. We have initiated a program to evaluate these forces in water and we report here our preliminary results.
Bibliography:ark:/67375/TPS-6MXPZX30-Z
istex:39E2C3E11F8C45A11C79454F81F962C9105BE228
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0002-7863
1520-5126
DOI:10.1021/ja00055a066