Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs - Steinebach, Christian; Bricelj, Aleša; Murgai, Arunima; Sosič, Izidor; Bischof, Luca; Ng, Yuen Lam Dora; Heim, Christopher; Maiwald, Samuel; Proj, Matic; Voget, Rabea; Feller, Felix; Košmrlj, Janez; et al. (Journal of medicinal chemistry, 2023)
Keywords: Chemistry, Medicinal; Life Sciences & Biomedicine; Pharmacology & Pharmacy; Science & Technology; MULTIPLE-MYELOMA; ANTIANGIOGENIC PROPERTIES; RECOGNITION; IMMOBILIZED ARTIFICIAL MEMBRANE; LENALIDOMIDE; DEGRADATION; FLUORINE; BROMODOMAIN; BINDING; HYDROGEN-BONDS