Heterologous and Engineered Biosynthesis of Nematocidal Polyketide–Nonribosomal Peptide Hybrid Macrolactone from Extreme Thermophilic Fungi - Zhang, Jin-Mei; Wang, Hang-Hang; Liu, Xuan; Hu, Chang-Hua; Zou, Yi (Journal of the American Chemical Society, 2020)
Keywords: Antinematodal Agents - metabolism; Aspergillus nidulans; Aspergillus nidulans - genetics; biosynthesis; catalytic activity; Chemistry; Chemistry, Multidisciplinary; Cyclization; enzymes; Escherichia coli; Escherichia coli - genetics; Esterification; genes; lactones; Lactones - metabolism; macrocyclization reactions; nematicidal properties; peptides; Peptides - metabolism; Physical Sciences; Polyketides - metabolism; Science & Technology; Talaromyces; Talaromyces - metabolism; thermophilic fungi; SYNTHASE; ELUCIDATION; METABOLITES; ACID; NATURAL-PRODUCTS; THERMOLIDES; GENES; GENERATION; TRANS