Candida albicans Promotes Oral Cancer via IL-17A/IL-17RA-Macrophage Axis

• Published in: mBio Vol. 14; no. 3; p. e0044723
• Main Authors: Wang, Xu, Wu, Shuangshaung, Wu, Wenjie, Zhang, Wenqing, Li, Linman, Liu, Qian, Yan, Zhimin
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 27.06.2023
• Subjects: Animals; Candida - metabolism; Candida albicans; Candida albicans - metabolism; Candidiasis; Host-Microbial Interactions; IL-17A; Interleukin-17; macrophage; Macrophages; Mice; Mice, Inbred C3H; Mouth Neoplasms; oral cancer; Research Article; Tumor Microenvironment; Candida albicans; macrophage; tumor microenvironment; IL-17A; oral cancer

The relationship between fungi and cancer is gradually receiving attention. Among them, some clinical evidence has shown that Candida may be a contributor to gastrointestinal cancers, especially oral cancer. The association between Candida albicans ( C. albicans ) and oral cancer (OC) has been notic...