Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis

• Published in: Infection and immunity Vol. 89; no. 4
• Main Authors: Gonzalez-Ferrer, Shekina, Peñaloza, Hernán F., Budnick, James A., Bain, William G., Nordstrom, Hayley R., Lee, Janet S., Van Tyne, Daria
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 17.03.2021
• Subjects: Animals; Disease Susceptibility; Geography, Medical; Global Health; Host-Pathogen Interactions - immunology; Humans; Immunity, Innate; Klebsiella Infections - epidemiology; Klebsiella Infections - immunology; Klebsiella Infections - microbiology; Klebsiella pneumoniae - drug effects; Klebsiella pneumoniae - pathogenicity; Klebsiella pneumoniae - physiology; Minireview; Population Surveillance; Virulence; Klebsiella; pathogenesis; evolution; innate immune system

Klebsiella pneumoniae are Gram-negative facultative anaerobes that are found within host-associated commensal microbiomes, but they can also cause a wide range of infections that are often difficult to treat. These infections are caused by different pathotypes of K. pneumoniae , called either classi...