Impact of Reinfection with SARS-CoV-2 Omicron Variants in Previously Infected Hamsters

• Published in: Journal of virology Vol. 97; no. 1; p. e0136622
• Main Authors: Shiwa-Sudo, Nozomi, Sakai, Yusuke, Iwata-Yoshikawa, Naoko, Watanabe, Shinji, Yamada, Souichi, Kuroda, Yudai, Yamamoto, Tsukasa, Shirakura, Masayuki, Fujisaki, Seiichiro, Miyazaki, Kaya, Miura, Hideka, Nagata, Shiho, Fukushi, Shuetsu, Maeda, Ken, Hasegawa, Hideki, Suzuki, Tadaki, Nagata, Noriyo
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 31.01.2023
• Subjects: Animals; COVID-19; Cricetinae; Host-Microbial Interactions; Mesocricetus; Pathogenesis and Immunity; Reinfection; RNA, Viral; SARS-CoV-2 - genetics; pathogenesis; SARS-CoV-2; reinfection; variants; animal model

The emergence of SARS-CoV-2 variants and the widespread use of COVID-19 vaccines has resulted in individual differences in immune status against SARS-CoV-2. A decay in immunity over time and the emergence of variants that partially evade the immune response can also lead to reinfection. The diversit...