The Emerging Role of β-Lactams in the Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infections

• Published in: Antimicrobial agents and chemotherapy Vol. 64; no. 7
• Main Authors: Molina, Kyle C., Morrisette, Taylor, Miller, Matthew A., Huang, Vanthida, Fish, Douglas N.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 23.06.2020
• Subjects: Editor's Pick; Minireview; ceftaroline; combination therapy; beta-lactams; Staphylococcus aureus bacteremia

Methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSI) are associated with substantial morbidity and mortality. Monotherapy with first-line antimicrobials such as vancomycin (VAN; glycopeptide) and daptomycin (DAP; lipopeptide) are inadequate in some cases due to reduced ant...