Anaerobic Microbiota Derived from the Upper Airways Impact Staphylococcus aureus Physiology

• Published in: Infection and immunity Vol. 89; no. 9; p. e0015321
• Main Authors: Lucas, Sarah K., Villarreal, Alex R., Ahmad, Madison M., Itabiyi, Abayo, Feddema, Erin, Boyer, Holly C., Hunter, Ryan C.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 16.08.2021
• Subjects: Anaerobiosis; Chronic Disease; Disease Susceptibility; Host-Associated Microbial Communities; Host-Pathogen Interactions; Humans; Microbial Ecology; Microbial Interactions; Microbiota; Respiratory Tract Infections - microbiology; Spotlight; Staphylococcal Infections - microbiology; Staphylococcus aureus - physiology; sinusitis; cross-feeding; anaerobes; mucin; Staphylococcus aureus

Staphylococcus aureus is associated with the development of persistent and severe inflammatory diseases of the upper airways. Yet, S. aureus is also carried asymptomatically in the sinonasal cavity of ∼50% of healthy adults. The causes of this duality and host and microbial factors that tip the bala...