Mapping the Internal Recognition Surface of an Octanuclear Coordination Cage Using Guest Libraries

• Published in: Journal of the American Chemical Society Vol. 136; no. 23; pp. 8475 - 8483
• Main Authors: Turega, Simon, Cullen, William, Whitehead, Martina, Hunter, Christopher A, Ward, Michael D
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 11.06.2014

Size and shape criteria for guest binding inside the cavity of an octanuclear cubic coordination cage in water have been established using a new fluorescence displacement assay to quantify guest binding. For aliphatic cyclic ketones of increasing size (from C5 to C11), there is a linear relationship...