Stereoelectronic Control in Diels−Alder Reaction of Dissymmetric 1,3-Dienes

• Published in: Accounts of chemical research Vol. 33; no. 5; pp. 278 - 286
• Main Authors: Mehta, Goverdhan, Uma, R
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 01.05.2000
• Subjects: Cyclopentanes - chemistry; Models, Molecular; Molecular Conformation; Molecular Structure; Quantum Theory

The Diels−Alder reaction is a widely employed protocol in which four stereogenic centers are generated in a predictable manner with olefin geometry, adjoining chiral center, and transition-state topology serving as the main controlling elements. However, when the Diels−Alder partners are in a dissym...