A Unique Aliphatic Tertiary Amine Chromophore: Fluorescence, Polymer Structure, and Application in Cell Imaging
Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been...
Saved in:
| Published in | Journal of the American Chemical Society Vol. 134; no. 51; pp. 20581 - 20584 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Chemical Society
26.12.2012
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been observed only in vapor phase. The objective of this study is how to retain the strong fluorescence of tertiary amines in polymers. Tertiary amines as branching units of the hyperbranched poly(amine-ester) (HypET) display relatively strong fluorescence (Φ = 0.11–0.43). The linear polymers with tertiary amines in the backbone or as the side group are only very weakly fluorescent. The tertiary amine of HypET is easily oxidized under ambient conditions, and red-shifting of fluorescence for the oxidized products has been observed. The galactopyranose-modified HypET exhibits low cytotoxicity and bright cell imaging. Thus, this study opens a new route of synthesizing fluorescent materials for cell imaging, biosensing, and drug delivery. |
|---|---|
| AbstractList | Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been observed only in vapor phase. The objective of this study is how to retain the strong fluorescence of tertiary amines in polymers. Tertiary amines as branching units of the hyperbranched poly(amine-ester) (HypET) display relatively strong fluorescence (Φ = 0.11-0.43). The linear polymers with tertiary amines in the backbone or as the side group are only very weakly fluorescent. The tertiary amine of HypET is easily oxidized under ambient conditions, and red-shifting of fluorescence for the oxidized products has been observed. The galactopyranose-modified HypET exhibits low cytotoxicity and bright cell imaging. Thus, this study opens a new route of synthesizing fluorescent materials for cell imaging, biosensing, and drug delivery. Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been observed only in vapor phase. The objective of this study is how to retain the strong fluorescence of tertiary amines in polymers. Tertiary amines as branching units of the hyperbranched poly(amine-ester) (HypET) display relatively strong fluorescence (Φ = 0.11-0.43). The linear polymers with tertiary amines in the backbone or as the side group are only very weakly fluorescent. The tertiary amine of HypET is easily oxidized under ambient conditions, and red-shifting of fluorescence for the oxidized products has been observed. The galactopyranose-modified HypET exhibits low cytotoxicity and bright cell imaging. Thus, this study opens a new route of synthesizing fluorescent materials for cell imaging, biosensing, and drug delivery.Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been observed only in vapor phase. The objective of this study is how to retain the strong fluorescence of tertiary amines in polymers. Tertiary amines as branching units of the hyperbranched poly(amine-ester) (HypET) display relatively strong fluorescence (Φ = 0.11-0.43). The linear polymers with tertiary amines in the backbone or as the side group are only very weakly fluorescent. The tertiary amine of HypET is easily oxidized under ambient conditions, and red-shifting of fluorescence for the oxidized products has been observed. The galactopyranose-modified HypET exhibits low cytotoxicity and bright cell imaging. Thus, this study opens a new route of synthesizing fluorescent materials for cell imaging, biosensing, and drug delivery. |
| Author | Pan, Cai-Yuan Sun, Miao Hong, Chun-Yan |
| AuthorAffiliation | University of Science and Technology of China |
| AuthorAffiliation_xml | – name: University of Science and Technology of China |
| Author_xml | – sequence: 1 givenname: Miao surname: Sun fullname: Sun, Miao – sequence: 2 givenname: Chun-Yan surname: Hong fullname: Hong, Chun-Yan – sequence: 3 givenname: Cai-Yuan surname: Pan fullname: Pan, Cai-Yuan email: pcy@ustc.edu.cn |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23215055$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkctKxDAUhoMoOl4WvoBkIyhYzaVpZ9yVwcvAgIK6Dpn01MmQJjVpF_P2RkddiODqJ-E7P8l39tG28w4QOqbkkhJGr1aKp-RFu4VGVDCSCcqKbTQihLCsHBd8D-3HuErHnI3pLtpjnFFBhBghX-EXZ94GwJU13VL1RuNnCL1RYY2r1jjA02Xwre-WPsA1vrVDyqjBabjAj96uWwj4qQ-D7oeQrpSrcdV11ujU5R02Dk_BWjxr1atxr4dop1E2wtFXHqCX25vn6X02f7ibTat5pnKa91k9IYoJKkReklzDGFQuGChNaFNrMtELTYqCMg3NgixyUTAOuqG1rkEBn9SEH6CzTW8XfPpd7GVr0qutVQ78ECVLMviElXn5L0pZyQuSQJ7Qky90WLRQyy6YNomS3z4TcLUBdPAxBmikNv2niD4oYyUl8mNj8mdjaeL818R36V_s6YZVOsqVH4JLCv_g3gEJBKGl |
| CitedBy_id | crossref_primary_10_1039_C6RA17068D crossref_primary_10_1021_acs_macromol_9b02109 crossref_primary_10_1021_acsmacrolett_3c00549 crossref_primary_10_1039_D2TA08457K crossref_primary_10_1016_j_inoche_2022_109836 crossref_primary_10_1016_j_xcrp_2020_100257 crossref_primary_10_1016_j_polymer_2016_11_018 crossref_primary_10_1039_D2TA00369D crossref_primary_10_1016_j_dyepig_2023_111255 crossref_primary_10_1021_acs_chemmater_5b00858 crossref_primary_10_1038_s41565_023_01405_3 crossref_primary_10_1039_C4RA09184A crossref_primary_10_1016_j_reactfunctpolym_2018_10_003 crossref_primary_10_1039_C6RA22916F crossref_primary_10_1002_macp_202400484 crossref_primary_10_1039_c3ra22680h crossref_primary_10_1021_acs_inorgchem_2c03441 crossref_primary_10_1002_ange_202312679 crossref_primary_10_1039_C5RA21580C crossref_primary_10_1002_anie_202117368 crossref_primary_10_1002_macp_201500537 crossref_primary_10_1039_D0TC01190H crossref_primary_10_1039_C4CS00528G crossref_primary_10_1002_app_46015 crossref_primary_10_1016_j_polymer_2017_02_039 crossref_primary_10_1016_j_molliq_2017_09_016 crossref_primary_10_1002_slct_201801263 crossref_primary_10_1360_SSC_2022_0052 crossref_primary_10_1021_acsami_7b17894 crossref_primary_10_1002_marc_202400073 crossref_primary_10_1021_acs_inorgchem_9b01084 crossref_primary_10_1002_anie_202204209 crossref_primary_10_1016_j_optmat_2023_113516 crossref_primary_10_1021_acsami_0c16657 crossref_primary_10_1039_C6PY01738J crossref_primary_10_1039_C4CS00224E crossref_primary_10_1002_pola_28416 crossref_primary_10_1039_C5OB01025J crossref_primary_10_1016_j_molliq_2020_113525 crossref_primary_10_1021_acs_langmuir_7b02614 crossref_primary_10_1002_marc_201400516 crossref_primary_10_1039_D1PY01437D crossref_primary_10_1039_D1RA08756H crossref_primary_10_1007_s10118_021_2630_z crossref_primary_10_1021_acs_iecr_0c02318 crossref_primary_10_1002_marc_202100321 crossref_primary_10_1016_j_bcab_2022_102577 crossref_primary_10_1002_pola_28420 crossref_primary_10_1002_chem_202300526 crossref_primary_10_1039_C6RA27390D crossref_primary_10_1002_ange_202214422 crossref_primary_10_1002_anie_202319003 crossref_primary_10_1016_j_matlet_2021_130115 crossref_primary_10_1002_pol_20210954 crossref_primary_10_1021_acs_macromol_8b00715 crossref_primary_10_1002_chem_201903935 crossref_primary_10_1002_marc_202400970 crossref_primary_10_1080_10408398_2023_2282677 crossref_primary_10_1039_C5RA13046H crossref_primary_10_1039_D3PY00559C crossref_primary_10_1246_cl_130877 crossref_primary_10_1002_ange_202117368 crossref_primary_10_1039_D2CC04902C crossref_primary_10_1021_acsmacrolett_3c00589 crossref_primary_10_1021_acsomega_9b03536 crossref_primary_10_1016_j_porgcoat_2021_106459 crossref_primary_10_1039_D0QM00626B crossref_primary_10_1002_marc_202000522 crossref_primary_10_1016_j_saa_2020_118732 crossref_primary_10_1021_acsami_0c23132 crossref_primary_10_1016_j_saa_2020_119261 crossref_primary_10_1021_acsaom_4c00498 crossref_primary_10_1016_j_molliq_2022_118878 crossref_primary_10_1021_acs_chemmater_3c00914 crossref_primary_10_1021_acs_chemmater_7b05206 crossref_primary_10_1021_acsabm_0c00718 crossref_primary_10_1002_adfm_202204263 crossref_primary_10_1002_marc_201700099 crossref_primary_10_1002_marc_201700530 crossref_primary_10_1002_anie_202410335 crossref_primary_10_1002_asia_201700234 crossref_primary_10_1021_acssuschemeng_2c07755 crossref_primary_10_1038_s41467_019_11190_0 crossref_primary_10_1039_D3NJ04004F crossref_primary_10_1002_anie_202413605 crossref_primary_10_1039_C4CC05342G crossref_primary_10_1039_C5CP07134H crossref_primary_10_1021_acs_biomac_8b00123 crossref_primary_10_1016_j_apsusc_2024_160196 crossref_primary_10_1021_jacs_9b08065 crossref_primary_10_1021_ma502352x crossref_primary_10_1021_acs_biomac_1c01396 crossref_primary_10_1246_cl_141156 crossref_primary_10_1039_C7ME00118E crossref_primary_10_1039_C4TB00905C crossref_primary_10_1007_s11426_017_9114_4 crossref_primary_10_1021_acs_biomac_8b01468 crossref_primary_10_1039_D1DT02964A crossref_primary_10_1021_acsami_8b15921 crossref_primary_10_1002_anie_201916591 crossref_primary_10_1002_cptc_202000090 crossref_primary_10_1002_VIW_20200135 crossref_primary_10_1039_C6RA19062F crossref_primary_10_1021_acsbiomaterials_9b01849 crossref_primary_10_1016_j_actbio_2017_01_019 crossref_primary_10_1039_D0SC05879C crossref_primary_10_1007_s00253_017_8325_2 crossref_primary_10_1016_j_dyepig_2023_111816 crossref_primary_10_1016_j_eurpolymj_2013_09_029 crossref_primary_10_1039_D2PY01173E crossref_primary_10_1002_ange_202413605 crossref_primary_10_1002_ange_201916591 crossref_primary_10_3390_molecules26216411 crossref_primary_10_1002_ange_202410335 crossref_primary_10_1016_j_snb_2020_129386 crossref_primary_10_1002_anie_202204383 crossref_primary_10_1002_adfm_202006944 crossref_primary_10_1021_acs_chemmater_0c02448 crossref_primary_10_1007_s11998_017_9957_y crossref_primary_10_1016_j_jphotochem_2017_09_050 crossref_primary_10_1016_j_mtchem_2021_100712 crossref_primary_10_1007_s10853_018_2867_2 crossref_primary_10_1002_anie_201504951 crossref_primary_10_1039_C5RA15570C crossref_primary_10_1016_j_jlumin_2021_118401 crossref_primary_10_3390_compounds3030032 crossref_primary_10_1016_j_cclet_2022_07_027 crossref_primary_10_1021_acs_macromol_9b02192 crossref_primary_10_1002_ange_202319003 crossref_primary_10_1039_C9MH01909J crossref_primary_10_1039_D2CC04852C crossref_primary_10_1002_ange_202204383 crossref_primary_10_1016_j_eurpolymj_2024_113671 crossref_primary_10_1021_acsami_0c15260 crossref_primary_10_1002_anie_202214422 crossref_primary_10_1007_s12274_014_0644_3 crossref_primary_10_1246_cl_190858 crossref_primary_10_1039_C9PY00519F crossref_primary_10_1007_s11237_023_09768_3 crossref_primary_10_1016_j_trac_2021_116308 crossref_primary_10_1002_pola_29334 crossref_primary_10_1016_j_snb_2019_126843 crossref_primary_10_1039_C4CS00229F crossref_primary_10_1002_adma_202205763 crossref_primary_10_1016_j_ceja_2020_100046 crossref_primary_10_1021_acs_macromol_1c02614 crossref_primary_10_1002_adom_201902176 crossref_primary_10_1016_j_toxlet_2017_03_022 crossref_primary_10_1039_C9PY00183B crossref_primary_10_1002_anie_202312679 crossref_primary_10_1002_marc_202100036 crossref_primary_10_1021_acsami_9b22475 crossref_primary_10_1002_mame_202000126 crossref_primary_10_1002_marc_201500572 crossref_primary_10_1021_acsmacrolett_9b00864 crossref_primary_10_1039_c3py01437a crossref_primary_10_1039_C4RA09081K crossref_primary_10_1002_smll_201601545 crossref_primary_10_1002_macp_202100425 crossref_primary_10_1039_C6TC02546C crossref_primary_10_1002_smll_201801560 crossref_primary_10_1021_acssuschemeng_2c01953 crossref_primary_10_1021_acs_bioconjchem_2c00208 crossref_primary_10_1021_acsami_9b04938 crossref_primary_10_1039_C9PY01686D crossref_primary_10_34133_research_0152 crossref_primary_10_1039_C6NR01909A crossref_primary_10_1021_acsami_1c19504 crossref_primary_10_1007_s11426_019_9704_y crossref_primary_10_1039_C5PY01537E crossref_primary_10_1002_pol_20220475 crossref_primary_10_1039_C7TC00868F crossref_primary_10_1002_cplu_202000021 crossref_primary_10_1016_j_molliq_2024_125290 crossref_primary_10_1021_ma502160w crossref_primary_10_1016_j_cej_2014_12_075 crossref_primary_10_1016_j_jphotochem_2019_112288 crossref_primary_10_1038_s41467_023_38769_y crossref_primary_10_1088_1757_899X_137_1_012003 crossref_primary_10_1039_C8QM00528A crossref_primary_10_1080_15685551_2017_1351728 crossref_primary_10_1021_acs_biomac_9b00051 crossref_primary_10_1016_j_tetlet_2019_04_016 crossref_primary_10_1021_acsami_1c18822 crossref_primary_10_1039_C6PY00654J crossref_primary_10_1021_acs_langmuir_8b00791 crossref_primary_10_1039_C5CP03658E crossref_primary_10_1021_acsapm_4c01624 crossref_primary_10_1007_s40242_021_0414_1 crossref_primary_10_1016_j_polymer_2025_128118 crossref_primary_10_1016_j_progpolymsci_2013_11_001 crossref_primary_10_1021_acsomega_8b00062 crossref_primary_10_1016_j_polymer_2021_124039 crossref_primary_10_1002_marc_202400307 crossref_primary_10_1002_adma_202300616 crossref_primary_10_1002_ange_202204209 crossref_primary_10_1016_j_polymer_2019_03_069 crossref_primary_10_1016_j_cej_2021_132142 crossref_primary_10_1021_acsabm_2c00337 crossref_primary_10_1039_D2PY00789D crossref_primary_10_1039_D0CS01087A crossref_primary_10_1021_acsomega_0c04700 crossref_primary_10_1002_advs_201700395 crossref_primary_10_1002_marc_202400657 crossref_primary_10_1002_pol_20200432 crossref_primary_10_1016_j_colsurfa_2017_01_064 crossref_primary_10_1007_s10118_015_1635_x crossref_primary_10_1016_j_xcrp_2020_100116 crossref_primary_10_1016_j_microc_2022_107224 crossref_primary_10_1016_j_progpolymsci_2018_09_004 crossref_primary_10_1016_j_polymer_2018_05_007 crossref_primary_10_1002_app_46723 crossref_primary_10_1002_macp_202100070 crossref_primary_10_1039_D2PY01581A crossref_primary_10_1002_adv_21688 crossref_primary_10_1016_j_reactfunctpolym_2023_105651 crossref_primary_10_1002_adhm_201900980 crossref_primary_10_1016_j_saa_2021_119604 crossref_primary_10_1039_C9SM00034H crossref_primary_10_1039_C5PY00836K crossref_primary_10_2139_ssrn_3960445 crossref_primary_10_1002_ange_201504951 crossref_primary_10_1039_C6CP05054A crossref_primary_10_1039_c4ra01726a crossref_primary_10_1039_C8MH01331D crossref_primary_10_1002_smll_202302095 crossref_primary_10_1039_c3py01513k crossref_primary_10_1039_C7PY00844A crossref_primary_10_1134_S107036322304031X crossref_primary_10_1021_acsami_2c19121 crossref_primary_10_1021_acs_macromol_0c01792 crossref_primary_10_1007_s41061_021_00326_w crossref_primary_10_1016_j_jcis_2017_02_029 crossref_primary_10_1039_D2MA00327A crossref_primary_10_1039_C4CC05806B |
| Cites_doi | 10.1021/ma00044a013 10.1002/marc.200900482 10.1002/marc.200800571 10.1016/0009-2614(71)85137-0 10.1038/nmeth1004-73 10.1016/0047-2670(81)85006-X 10.1039/P29850001069 10.1021/ja0454992 10.1103/PhysRevLett.98.253004 10.1039/an9830801067 10.1126/science.276.5321.2012 10.1038/nbt767 10.1021/jp8041236 10.1021/nn800590n 10.1073/pnas.0900004106 10.1016/0009-2614(71)80580-8 10.1016/0169-409X(94)90007-8 10.1021/bm1014816 10.1038/nchem.334 10.1021/ja0475914 10.1021/ja068452k 10.1002/macp.200700581 10.1366/0003702011952596 10.1021/ja00812a021 10.1038/nchembio.69 10.1039/p29850001063 |
| ContentType | Journal Article |
| Copyright | Copyright © 2012 American Chemical
Society |
| Copyright_xml | – notice: Copyright © 2012 American Chemical Society |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 |
| DOI | 10.1021/ja310236m |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE AGRICOLA MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1520-5126 |
| EndPage | 20584 |
| ExternalDocumentID | 23215055 10_1021_ja310236m a674095833 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | - .K2 02 4.4 53G 55A 5GY 5RE 5VS 7~N 85S AABXI ABFLS ABMVS ABPPZ ABPTK ABUCX ABUFD ACGFS ACJ ACNCT ACS AEESW AENEX AETEA AFEFF ALMA_UNASSIGNED_HOLDINGS AQSVZ BAANH BKOMP CS3 DU5 DZ EBS ED ED~ EJD ET F5P GNL IH9 JG JG~ K2 LG6 P2P ROL RXW TAE TAF TN5 UHB UI2 UKR UPT VF5 VG9 VQA W1F WH7 X XFK YZZ ZHY --- -DZ -ET -~X .DC AAHBH AAYXX ABBLG ABJNI ABLBI ABQRX ACBEA ACGFO ADHLV AGXLV AHDLI AHGAQ CITATION CUPRZ GGK IH2 XSW YQT ZCA ~02 CGR CUY CVF ECM EIF NPM YIN 7X8 7S9 L.6 |
| ID | FETCH-LOGICAL-a414t-d90a251554704ce8ea452eac01fdc09cbc06612cefb0b45623ecf1dcdeae39d03 |
| IEDL.DBID | ACS |
| ISSN | 0002-7863 1520-5126 |
| IngestDate | Thu Jul 10 17:48:14 EDT 2025 Fri Jul 11 12:02:26 EDT 2025 Wed Feb 19 01:53:26 EST 2025 Tue Jul 01 02:08:37 EDT 2025 Thu Apr 24 22:56:05 EDT 2025 Thu Aug 27 13:50:41 EDT 2020 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 51 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-a414t-d90a251554704ce8ea452eac01fdc09cbc06612cefb0b45623ecf1dcdeae39d03 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 23215055 |
| PQID | 1273604733 |
| PQPubID | 23479 |
| PageCount | 4 |
| ParticipantIDs | proquest_miscellaneous_2000392747 proquest_miscellaneous_1273604733 pubmed_primary_23215055 crossref_citationtrail_10_1021_ja310236m crossref_primary_10_1021_ja310236m acs_journals_10_1021_ja310236m |
| ProviderPackageCode | JG~ 55A AABXI GNL VF5 7~N ACJ VG9 W1F ACS AEESW AFEFF .K2 ABMVS ABUCX IH9 BAANH AQSVZ ED~ UI2 CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2012-12-26 |
| PublicationDateYYYYMMDD | 2012-12-26 |
| PublicationDate_xml | – month: 12 year: 2012 text: 2012-12-26 day: 26 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of the American Chemical Society |
| PublicationTitleAlternate | J. Am. Chem. Soc |
| PublicationYear | 2012 |
| Publisher | American Chemical Society |
| Publisher_xml | – name: American Chemical Society |
| References | Cardoza Job D. (ref10/cit10a) 2008; 112 Yang W. (ref15/cit15) 2011; 12 Wang D. (ref11/cit11a) 2004; 126 Gruber A. (ref13/cit13) 1997; 276 Jaiswal Jyoti K. (ref2/cit2c) 2004; 1 Pucci A. (ref3/cit3b) 2008; 209 Beecroft Richard A. (ref5/cit5) 1985 Wu C. (ref2/cit2a) 2008; 2 Zhu L. (ref2/cit2b) 2007; 129 Muto Y. (ref9/cit9) 1971; 9 Jaiswal Jyoti K. (ref2/cit2d) 2003; 21 Beecroft Richard A. (ref6/cit6) 1985 Halprrn Arthur M. (ref8/cit8) 1981; 15 Yang W. (ref12/cit12) 2009; 30 Meltzer A. Donald (ref17/cit17) 1992; 25 Freeman C. G. (ref4/cit4) 1971; 8 Larson Charlotte L. (ref16/cit16) 2001; 55 Minitti Michael P. (ref10/cit10b) 2007; 98 Seymour Len W. (ref20/cit20) 1994; 14 ref19/cit19 Lee W. I. (ref11/cit11b) 2004; 126 Domaille Dylan W. (ref1/cit1a) 2008; 4 Yang J. Y. (ref3/cit3a) 2009; 106 Chu C. C. (ref18/cit18) 2009; 30 Halpern Arthur M. (ref7/cit7) 1974; 96 Williams Alun T. R. (ref14/cit14) 1983; 108 De M. (ref1/cit1b) 2009; 1 |
| References_xml | – volume: 25 start-page: 4541 year: 1992 ident: ref17/cit17 publication-title: Macromolecules doi: 10.1021/ma00044a013 – volume: 30 start-page: 2096 year: 2009 ident: ref12/cit12 publication-title: Macromol. Rapid Commun. doi: 10.1002/marc.200900482 – volume: 30 start-page: 89 year: 2009 ident: ref18/cit18 publication-title: Macromol. Rapid Commun. doi: 10.1002/marc.200800571 – volume: 9 start-page: 597 year: 1971 ident: ref9/cit9 publication-title: Chem. Phys. Lett. doi: 10.1016/0009-2614(71)85137-0 – volume: 1 start-page: 73 year: 2004 ident: ref2/cit2c publication-title: Nat. Methods doi: 10.1038/nmeth1004-73 – volume: 15 start-page: 147 year: 1981 ident: ref8/cit8 publication-title: J. Photochem. doi: 10.1016/0047-2670(81)85006-X – start-page: 1069 year: 1985 ident: ref5/cit5 publication-title: J. Chem. Soc., Perkin Trans. 2 doi: 10.1039/P29850001069 – volume: 126 start-page: 13204 year: 2004 ident: ref11/cit11a publication-title: J. Am. Chem. Soc. doi: 10.1021/ja0454992 – volume: 98 start-page: 253004 year: 2007 ident: ref10/cit10b publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.98.253004 – volume: 108 start-page: 1067 year: 1983 ident: ref14/cit14 publication-title: Analyst doi: 10.1039/an9830801067 – volume: 276 start-page: 2012 year: 1997 ident: ref13/cit13 publication-title: Science doi: 10.1126/science.276.5321.2012 – volume: 21 start-page: 47 year: 2003 ident: ref2/cit2d publication-title: Nat. Biotechnol. doi: 10.1038/nbt767 – volume: 112 start-page: 10736 year: 2008 ident: ref10/cit10a publication-title: J. Phys. Chem. A doi: 10.1021/jp8041236 – volume: 2 start-page: 2415 year: 2008 ident: ref2/cit2a publication-title: ACS Nano doi: 10.1021/nn800590n – ident: ref19/cit19 – volume: 106 start-page: 10086 year: 2009 ident: ref3/cit3a publication-title: Proc. Natl Acad. Sci. U.S.A. doi: 10.1073/pnas.0900004106 – volume: 8 start-page: 77 year: 1971 ident: ref4/cit4 publication-title: Chem. Phys. Lett. doi: 10.1016/0009-2614(71)80580-8 – volume: 14 start-page: 89 year: 1994 ident: ref20/cit20 publication-title: Adv. Drug Delivery Rev. doi: 10.1016/0169-409X(94)90007-8 – volume: 12 start-page: 1523 year: 2011 ident: ref15/cit15 publication-title: Biomacromolecules doi: 10.1021/bm1014816 – volume: 1 start-page: 461 year: 2009 ident: ref1/cit1b publication-title: Nat. Chem. doi: 10.1038/nchem.334 – volume: 126 start-page: 8358 year: 2004 ident: ref11/cit11b publication-title: J. Am. Chem. Soc. doi: 10.1021/ja0475914 – volume: 129 start-page: 3524 year: 2007 ident: ref2/cit2b publication-title: J. Am. Chem. Soc. doi: 10.1021/ja068452k – volume: 209 start-page: 900 year: 2008 ident: ref3/cit3b publication-title: Macromol. Chem. Phys. doi: 10.1002/macp.200700581 – volume: 55 start-page: 679 year: 2001 ident: ref16/cit16 publication-title: Appl. Spectrosc. doi: 10.1366/0003702011952596 – volume: 96 start-page: 1393 year: 1974 ident: ref7/cit7 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja00812a021 – volume: 4 start-page: 168 year: 2008 ident: ref1/cit1a publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.69 – start-page: 1063 year: 1985 ident: ref6/cit6 publication-title: J. Chem. Soc., Perkin Trans. 2 doi: 10.1039/p29850001063 |
| SSID | ssj0004281 |
| Score | 2.5227442 |
| Snippet | Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for... |
| SourceID | proquest pubmed crossref acs |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 20581 |
| SubjectTerms | cytotoxicity Dendrimers - analysis drugs Fluorescence fluorescent dyes Fluorescent Dyes - analysis Hep G2 Cells Humans image analysis Microscopy, Confocal photoluminescence Polyamines - analysis Polyesters - analysis polymers tertiary amines vapors |
| Title | A Unique Aliphatic Tertiary Amine Chromophore: Fluorescence, Polymer Structure, and Application in Cell Imaging |
| URI | http://dx.doi.org/10.1021/ja310236m https://www.ncbi.nlm.nih.gov/pubmed/23215055 https://www.proquest.com/docview/1273604733 https://www.proquest.com/docview/2000392747 |
| Volume | 134 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV3JTsMwEB2xHODCvpRNZjlwIFXiOEnLLSpUgARCgkrcKi8TgchSlfYAX884bVgEhVOkaCInnnH8RuN5D-BImzDwlPYcKREd4RntEE6WjlKKa65cKRJb0b2-CS864uoheJiCwwkVfG75gXxLLxBm0zDLQ1q8Fv-07j6bH3nDqzBu1Aj9ij7o66N269Ev37eeCXiy3Ffai3BWdeeMjpM814cDVddvP8ka_3rlJVgY40oWjwJhGaYwX4G5ViXntgpFzDolWSuL06feoyVqZff2ULXsv7I4I7DJLFFuVvQeiz6esnY6pKvletJ4wm6L9DXDPrsr6WaHfbolc8Piz_I3e8pZC9OUXWal8NEadNrn960LZ6y24EjhiYFjmq7kVvBFRK7Q2EApAk6_ZddLjHabWmlCJx7XmChX2bzJR52Qbw1K9JvG9ddhJi9y3ARmgsSgCnVTRtwmRKohEyGQqyjQgZSmBnvkju54tbx0y0I4p0SkmrcaHFee6uoxV7mVzEh_Mz34MO2NCDp-M9qv3N2labc1EZljMaShCb6Froh8f7INLzuYbfpeg41RrHwMRYCUIHUQbP33SdswT1irFJLh4Q7MkLtwl_DMQO2V8fwOtHDwUw |
| linkProvider | American Chemical Society |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1JT-swELZYDnBhefCgrOaJA4cXlDhO0nKLKqqyColW4hZ5mQhElqrLAX49YzehjycQnCJFk3iZSfyNxv4-Qo6VDgNPKs8RAsDhnlYO4mThSCmZYtIVPDUV3ZvbsNvnlw_BQ0WTY87CYCdG-KaRLeLP2AUMTZBvWAbCfJ4sIghhJprj9v3sDCRrejXUjZqhX7MI_fuoWYHU6OMK9AWstMtLZ3WqU2Q7ZneVPJ9OxvJUvf7H2fiznq-RlQpl0ngaFutkDopfZKldi7ttkDKmfUvdSuPsafBoaFtpz2yxFsMXGucIPamhzc3LwWM5hDPaySZ4NcxPCv7SuzJ7yWFI7y357GSIt0ShaTwrhtOngrYhy-hFbmWQNkm_c95rd51Ke8ER3ONjR7dcwYz8C49crqAJggcMf9Kul2rltpRUiFU8piCVrjRZlA8qRU9rEOC3tOv_JgtFWcA2oTpINchQtUTETHokmyLlHJiMAhUIoRvkAKctqb6dUWLL4gzTknreGuSkdliiKuZyI6CRfWb65910MKXr-MzoqPZ6gtNuKiSigHKCTSOYC10e-f7XNsyeZzbJfINsTUPmvSmEpwiwg2DnuyEdkqVu7-Y6ub64vdoly4jCrMQMC_fIAroO9hHpjOWBDfE3_wz4tA |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9RADLagSMClvOnyKAPiwIFUyWSS7HKLFlYtj1KpXam3aB6OWpHHah-H8uuxZ5MtoFZwihQ5GWfsiT_LM58B3lqXJpGxUaA1YqAiZwPCyTowxkgrTahVyRXdb4fp_lR9Pk1Ou0SRz8KQEgt608IX8XlVz1zZMQwwVVDMTANpfRNucbmOPTofH1-eg5TDqIe72TCNeyah3x_lKGQXf0aha6ClDzGTe_B9o5zfWfJjb7U0e_bnX7yN_6_9fdju0KbI1-7xAG5g8xDujPsmb4-gzcXUU7iKvDqfnTF9qzjhrdZ6fiHymiCoYPrcup2dtXP8ICbViq7MAGXxvThqq4sa5-LYk9Cu5nRLN07kl0Vxcd6IMVaVOKh9O6THMJ18OhnvB10PhkCrSC0DNwq15DYwKguVxSFqlUj6WYdR6Ww4ssYSZomkxdKEhrOpGG1JFneoMR65MH4CW03b4A4Il5QOTWpHOpOcJpmhLpVCabLEJlq7AezS1BXdGloUvjwuKT3p520A73qjFbZjMOdGGtVVom82orM1bcdVQq97yxc07Vwp0Q22KxqaQF0aqiyOr5eR_lwzJ_UDeLp2m81QBFMJaCfJs3990iu4ffRxUnw9OPzyHO4SGPOdZmT6ArbIcviSAM_S7Hov_wUad_s3 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+unique+aliphatic+tertiary+amine+chromophore%3A+fluorescence%2C+polymer+structure%2C+and+application+in+cell+imaging&rft.jtitle=Journal+of+the+American+Chemical+Society&rft.au=Sun%2C+Miao&rft.au=Hong%2C+Chun-Yan&rft.au=Pan%2C+Cai-Yuan&rft.date=2012-12-26&rft.issn=1520-5126&rft.eissn=1520-5126&rft.volume=134&rft.issue=51&rft.spage=20581&rft_id=info:doi/10.1021%2Fja310236m&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-7863&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-7863&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-7863&client=summon |