Anodic Oxidation for the Stereoselective Synthesis of Heterocycles

• Published in: Accounts of chemical research Vol. 53; no. 1; pp. 105 - 120
• Main Authors: Yamamoto, Kosuke, Kuriyama, Masami, Onomura, Osamu
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 21.01.2020
• Subjects: Electrodes; Heterocyclic Compounds - chemical synthesis; Heterocyclic Compounds - chemistry; Molecular Structure; Oxidation-Reduction; Stereoisomerism

Conspectus Stereodefined aliphatic heterocycles are one of the fundamental structural motifs observed in natural products and biologically active compounds. Various strategies for the synthesis of these building blocks based on transition metal catalysis, organocatalysis, and noncatalytic conditions...