Poly(2-oxazoline) Hydrogels for Controlled Fibroblast Attachment

• Published in: Biomacromolecules Vol. 14; no. 8; pp. 2724 - 2732
• Main Authors: Farrugia, Brooke L, Kempe, Kristian, Schubert, Ulrich S, Hoogenboom, Richard, Dargaville, Tim R
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 12.08.2013
• Subjects: Amino Acid Sequence; Applied sciences; Biological and medical sciences; Cell Adhesion; Cell Shape; Cells, Cultured; Exact sciences and technology; Fibroblasts - physiology; Humans; Hydrogels - chemical synthesis; Hydrogels - chemistry; Medical sciences; Oligopeptides - chemistry; Organic polymers; Oxazoles - chemistry; Physicochemistry of polymers; Properties and characterization; Solution and gel properties; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; Cationic copolymerization; Encapsulation; Photochemical crosslinking; Peptides; Tissue engineering; Photochemical reaction; Experimental study; Sulfur copolymer; Lateral group; Colloidal gel; Chemical modification; Mercaptoalcohol; Preparation; Cell adhesion; Addition reaction; Biomaterial; Ethyleneimine derivative copolymer; Ring opening copolymerization; Fibroblast

Currently there is a lack of choice when selecting synthetic materials with the cell-instructive properties demanded by modern biomaterials. The purpose of this study was to investigate the attachment of cells onto hydrogels prepared from poly(2-oxazoline)s selectively functionalized with cell adhes...