Rethinking Data Collection and Signal Processing. 2. Preserving the Temporal Fidelity of Electrochemical Measurements

• Published in: Analytical chemistry (Washington) Vol. 85; no. 16; pp. 7654 - 7658
• Main Authors: Atcherley, Christopher W, Vreeland, Richard F, Monroe, Eric B, Sanchez-Gomez, Esther, Heien, Michael L
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 20.08.2013
• Subjects: Analytical chemistry; Animals; Background noise; Constants; Data Collection; Electrochemical Techniques - standards; Exocytosis; Filtering; Fourier Analysis; Kinetics; Mathematical analysis; Molecular chemistry; Noise; PC12 Cells; Phase (cyclic); Preserving; Rats; Signal Processing, Computer-Assisted; Signal to noise ratio; Signal transduction; Symbols; Waveform analysis

Direct electrochemical measurements of biological events are often challenging because of the low signal relative to the magnitude of the background and noise. When choosing a data processing approach, the frequency and phase content of the data must be considered. Here, we employ a zero-phase (infi...