Elevated Serum Polybrominated Diphenyl Ethers and Thyroid-Stimulating Hormone Associated with Lymphocytic Micronuclei in Chinese Workers from an E-Waste Dismantling Site

• Published in: Environmental science & technology Vol. 42; no. 6; pp. 2195 - 2200
• Main Authors: Yuan, Jing, Chen, Lan, Chen, Duohong, Guo, Huan, Bi, Xinhui, Ju, Ying, Jiang, Pu, Shi, Jibin, Yu, Zhiqiang, Yang, Jin, Li, Liping, Jiang, Qi, Sheng, Guoying, Fu, Jiamo, Wu, Tangchun, Chen, Xuemin
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 15.03.2008
• Subjects: Adult; Applied sciences; Asian Continental Ancestry Group; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - urine; DNA; Ecotoxicology and Human Environmental Health; Electronics; Environmental Monitoring; Environmental Pollutants - blood; Environmental Pollutants - toxicity; Exact sciences and technology; Female; Flame Retardants - metabolism; Flame Retardants - toxicity; Glutathione - blood; Humans; Lymphocytes - drug effects; Male; Malondialdehyde - blood; Micronuclei, Chromosome-Defective - chemically induced; Occupational Exposure - adverse effects; Occupational Exposure - analysis; Phenyl Ethers - blood; Phenyl Ethers - toxicity; Pollution; Polybrominated Biphenyls - blood; Polybrominated Biphenyls - toxicity; Superoxide Dismutase - blood; Thyrotropin - blood; Waste Products; China, People's Rep; Persistent organic pollutant; Village; Risk factor; Flame retardant; Lipids; Volatile organic compound; Oxidation; Electronic scrap; Low volatile compound; Organic compounds; Confidence interval

In this study, we recruited 49 subjects from one village close to an electronic waste (e-waste) site (exposed group) and another located 50 km away from the e-waste site (control group). We found that serum levels of polybrominated diphenyl ethers (median PBDEs, 382 ng/g lipid weight; range, 77–8452...