Interrogating the Crucial Interactions at Play in the Chiral Cation-Directed Enantioselective Borylation of Arenes

• Published in: ACS catalysis Vol. 13; no. 19; pp. 13043 - 13055
• Main Authors: Ermanis, Kristaps, Gibson, David C., Genov, Georgi R., Phipps, Robert J.
• Format: Journal Article
• Language: English
• Published: American Chemical Society 06.10.2023
• Subjects: iridium; chiral cation; C–H borylation; noncovalent interaction; computational chemistry

Rendering a common ligand scaffold anionic and then pairing it with a chiral cation represents an alternative strategy for developing enantioselective versions of challenging transformations, as has been recently demonstrated in the enantioselective borylation of arenes using a quinine-derived chira...